jupiter

Jupiter R&D autoclavable Fermenters/Bioreactors

JUPITER is designed as entry-level fermenter for easy control by beginners and experienced user alike. It is therefore ideal for educational purposes. JUPITER meets your specific needs; it covers a wide range of applications and complies with the requirements of a validated GMP regulation.

  • User-friendly fermentation and cultivation management
  • Innovative Parallel process control
  • Left and right pumps orientations to maximize lab space efficiency
  • Remote control for after sale assistance
  • Remote access via PC or tablet
  • Parallel parameters calibration
  • dO2 and pH cascade feature
  • Up to 4 integrated pumps capable of operating in variable speed mode + additional externals brushless pumps
  • Automatic gas mixing algorithms for simplified controls (4-gas, 3-gas, O2 enrichment, N2 enrichment)
  • Safety: pressure releaf valve included with every unit.
  • Powerful brushless motors, from 1 to 2000 RPM.
  • Online absorbed Torques (Nm) and Power (W) measurements obtaining an indirect density indication of the culture broth.
  • 23’’ touch display.
  • Fully removable and cleanable jacket.
  • Up to 24 vessels managed with one station.
  • Modbus Hamilton sensors: pH, dO2, conductivity, redox.
  • LEDA Sampling System.
  • Sterile single use sampling system up to 180 sterile sampling per batch.
  • Needlefree connector is designed to reduce the risk of contamination during sampling
  • Sterile syringes (3-5-10-30 ml) with non return valve to guarantee the sterility of your samples.

Vessel

Solaris Code Jupiter 2.0 Jupiter 3.0 Jupiter 3.1 Jupiter 4.0 Jupiter 4.2 Jupiter 4.5 Jupiter 5.0 Jupiter 5.5 Jupiter 6.0 Jupiter 7.0 Jupiter 8.0 Jupiter 10.0
Production Code A1 B1 A2 A3 B2 C1 A4 B3 C2 B4 C3 C4
Total Volume (liters) 2,00 3,00 3,10 4,00 4,20 4,50 5,00 5,50 6,00 7,00 8,00 10,00
Ratio D/H 1:2,0 1:1,5 1:2,5 1:3,0 1:2,0 1:1,5 1:4,0 1:2,5 1:2,0 1:3,5 1:2,0 1:3,0
Min. Working Volume (liters) 0,33 0,40 0,46 0,46 0,72 0,44 0,46 0,72 0,87 0,62 0,87 0,96
Max. Working Volume (liters) 1,50 2,25 2,25 3,00 3,15 3,40 3,75 4,00 4,50 5,25 6,00 7,50
Max Temp. 0 – 135°C
Operating pressure < 0.5 bar
n. 16 Headplate Ports n.1 port, Gas Sparger Input n.1 port, Harvesting system n.1 port, dO₂ sensor
n.1 port, Gas overlay n.1 port, Temperature Sensor n.4 port, Sterile connections
n.1 port, Gas Out/Condenser n.1 port, Antifoam probe n.3 port, spares
n. 1 port, Sampling system n.1 port, pH sensor n.1 port, Agitation Group

Sensors length (mm)

pH 225 225 325 325 325 225 425 325 325 425 325 425
dO₂ 225 225 325 325 325 225 425 325 325 425 325 425

Dimensions for autoclave (with Condenser)

Height (mm) 505 505 580 655 580 505  760 655 580 760 655 760
Diameter (mm 225 240 225 225 240 280 225 240 280 240 280 280
Design Borosilicate Glass Jacketed Vessel
Materials Borosilicate Glass and AISI 316 L

Stirring

Drive Brushless Motor, Direct Assembly , 1-2000 rpm (bacterial), 1-500 (cell cultures)
Power 266 W
Impellers Select from: Rushtons impellers, Marine Impellers, Pitched blade

Thermoregulation

Control PID Control – Accuracy 0,1 °C – Jacket water heater

Gas Control & Gas Mixing

Sparger and overlay Gas Control Rotameter or TMFC
Gas Mixing (Air,CO2,O2,N2) n° of Rotameters, n.1 TMFC + n.4 solenoid valves, n° of TMFC
Sparger type Select from: Toro type (ring), syntered microbubbling both provided with 0,2 µm filter
Exhaust Condenser and 0,2 µm filter

Peristaltic Pumps

up to 4 Watson Marlow 114, speed 0 – 60 rpm, volumetric flow 0,5-51 ml/min, application assignable from software
n.1 Watson Marlow 313 FDM/D, speed 45-350 rpm, volumetric flow 1,5-1750 ml/min, application assignable from software n.
Watson Marlow 520 FDM/R2, speed 45-230 rpm, volumetric flow 1,8-3450 ml/min, application assignable from software

Controller

Master Controle Module from 1 to 4 units – Dimensions Height: 350 mm Largeness: 350 mm Depth: 350 mm
HMI with Leonardo software 9,7”
Temperature
Sensor PT100
Control system Measuring resident in Leonardo 2.0 software
Control range 0 – 150°C
pH
Sensor Digital Hamilton sensor
Control system Measuring resident in Leonardo 2.0 software
Control range 0 – 14
Operation temperature 0 – 130°C
Pressure range 0 – 6 bar
Actuator Cascade to peristlatic pumps for the addition of acid/base solutions or gas (CO2)
dO2
Sensor Digital Optical Hamilton sensor
Control system Measuring resident in Leonardo 2.0 software
Control range 0,05 – 300% air saturation
Operation temperature -10 – 130°C
Pressure range 0 – 12 bar
Actuator Cascade to RPM, Gas Control, feedings,ect
dCO2
Sensor Mettler Toledo sensor
Control system Measuring resident in Leonardo 2.0 software
Control range 0,00-200% saturation
Operation temperature -20.0-150°C
Pressure range 0 – 4 bar
Turbidity
Sensor Mettler Toledo sensor
Control system Measuring resident in Leonardo 2.0 software
Control range 0-250 g/L, 10-4000 FTU
Cell density
Sensor Hamilton-Fogale sensor
Control system Measuring resident in Leonardo 2.0 software
Option 1 Total cell density (Two ranges: 10^5 to 10^8 mammalian cells/ml – 0.5 to 300 g/L dry weight)
Option 2 Viable cell density (Two ranges: 5×10^5 to 8×10^8 mammalian cells/ml – 5 to 200 g/L dry weight)
Redox (ORP)
Sensor Digital Hamilton sensor
Control system Measuring resident in Leonardo 2.0 software
Control range ±2000 mV
Operation temperature – 10 -130°C
Pressure range ≤ 6 bar
Conductivity
Sensor Digital Hamilton sensor
Control system Measuring resident in Leonardo 2.0 software
Control range 1 – 3000 μS/cm
Operation temperature 0 -130°C
Pressure range 0 – 20 bar
Weight
Sensor n.3 load cells
Control Measuring resident in Leonardo 2.0 software
Antifoam/Level
Sensor Solaris sensor
Control Measuring resident in Leonardo 2.0 software